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HBV and HCV-associated Liver Cancer: Important Insights from the Genome

Author: Ritu Saxena, PhD Updated on July 5, 2013 (research article published in New England Journal of Medicine regarding the role of SALL4 gene in aggressive hepatocellular carcinoma) Hepatocellular...

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Mitochondria: More than just the “powerhouse of the cell”

Author and Curator: Ritu Saxena, Ph.D. Consultants: Aviva Lev-Ari, PhD, RN and Pnina G. Abir-Am, PhD CONTENT: Section I   : Mitochondrial diseases and molecular understanding Section II  : Diagnosis...

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Mitochondrial mutation analysis might be “1-step” away

Author and Reporter: Ritu Saxena, Ph.D. On 5th of July, I  discussed a general overview of varied mitochondrial functions, diseases, diagnosis and the current research focused on treatment of...

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Hold on. Mutations in Cancer do good.

Reporter: Prabodh Kandala, PhD A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers,...

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Rewriting the Mathematics of Tumor Growth; Teams Use Math Models to Sort...

Rewriting the Mathematics of Tumor Growth[1]; Teams Use Math Models to Sort Drivers from Passengers[2]:  Two JNCI Reviews by Mike Martin Regarding Genomics, Cancer, and Mutation Curator: Stephen J....

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Personalized medicine-based diagnostic test for NSCLC

FDA approves EGFR mutation detection test for NSCLC drug, Tarceva Author/Reporter: Ritu Saxena, Ph.D. The cobas EGFR Mutation Test, Roche Molecular Diagnostics, identifies mutations in epidermal growth...

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Exosomes

Exosomes Larry H. Bernstein, MD, FCAP, Curator LPBI   Human Exomes Galore A new database includes complete sequences of protein-coding DNA from 60,706 individuals. By Karen Zusi | November 16, 2015...

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Recent Progress in Gene Editing Error Reduction

Recent Progress in Gene Editing Error Reduction Larry H. Bernstein, MD, FCAP, Curator LPBI   Advances in Genome Editing Researchers develop a CRISPR-based technique that efficiently corrects point...

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Coronavirus mutation-does it matter?

Coronavirus mutation-does it matter? Reporter : Irina Robu, PhD Soon after SARS-CoV-2 was detected in China, scientists began analyzing viral sample and posting the genetic codes online. Mutations...

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