HBV and HCV-associated Liver Cancer: Important Insights from the Genome
Author: Ritu Saxena, PhD Updated on July 5, 2013 (research article published in New England Journal of Medicine regarding the role of SALL4 gene in aggressive hepatocellular carcinoma) Hepatocellular...
View ArticleMitochondria: More than just the “powerhouse of the cell”
Author and Curator: Ritu Saxena, Ph.D. Consultants: Aviva Lev-Ari, PhD, RN and Pnina G. Abir-Am, PhD CONTENT: Section I : Mitochondrial diseases and molecular understanding Section II : Diagnosis...
View ArticleMitochondrial mutation analysis might be “1-step” away
Author and Reporter: Ritu Saxena, Ph.D. On 5th of July, I discussed a general overview of varied mitochondrial functions, diseases, diagnosis and the current research focused on treatment of...
View ArticleHold on. Mutations in Cancer do good.
Reporter: Prabodh Kandala, PhD A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers,...
View ArticleRewriting the Mathematics of Tumor Growth; Teams Use Math Models to Sort...
Rewriting the Mathematics of Tumor Growth[1]; Teams Use Math Models to Sort Drivers from Passengers[2]: Two JNCI Reviews by Mike Martin Regarding Genomics, Cancer, and Mutation Curator: Stephen J....
View ArticlePersonalized medicine-based diagnostic test for NSCLC
FDA approves EGFR mutation detection test for NSCLC drug, Tarceva Author/Reporter: Ritu Saxena, Ph.D. The cobas EGFR Mutation Test, Roche Molecular Diagnostics, identifies mutations in epidermal growth...
View ArticleExosomes
Exosomes Larry H. Bernstein, MD, FCAP, Curator LPBI Human Exomes Galore A new database includes complete sequences of protein-coding DNA from 60,706 individuals. By Karen Zusi | November 16, 2015...
View ArticleRecent Progress in Gene Editing Error Reduction
Recent Progress in Gene Editing Error Reduction Larry H. Bernstein, MD, FCAP, Curator LPBI Advances in Genome Editing Researchers develop a CRISPR-based technique that efficiently corrects point...
View ArticleCoronavirus mutation-does it matter?
Coronavirus mutation-does it matter? Reporter : Irina Robu, PhD Soon after SARS-CoV-2 was detected in China, scientists began analyzing viral sample and posting the genetic codes online. Mutations...
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